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Ama-Oxynitrilase (HNL)
Mayelana nama-oxynitrilase
Ama-ES-HNL: I-enzyme yeklasi ekhuthaza ngokungeziwe ukungezwa kwe-HCN kuma-aldehydes (ama-ketone) ukuze kutholakale uhlobo lwe-R noma lwe-S lwe-cyanide alcohols, olungaguqulwa kalula lube izinhlobo eziningi zezidakamizwa noma izidakamizwa ngokusebenzisa indlela yamakhemikhali.
Kunezinhlobo ezingu-29 zemikhiqizo ye-oxynitrilase (Inombolo njenge-ES-HNL-101～ES-HNL-129) eyathuthukiswa yi-SyncoZymes. I-SZ-HNL iyithuluzi eliwusizo lokwenziwa kwe-regio- kanye ne-stereo-selective yama-(R)-cyanohydrins noma (S)-cyanohydrins avela ezinhlobonhlobo ze-aldehydes noma ngisho nama-ketone anuka kamnandi, aliphatic kanye ne-heterocyclic.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Nitro reductase (NTR)
Mayelana ne-nitro reductase
Ama-ES-NTR: Ama-flavoenzyme akhuthaza ukwehla okuncike ku-NAD(P)H kwamaqembu e-nitro kuma-compound e-nitroaromatic kanye ne-nitroheterocyclic abe yi-hydroxylamino kanye/noma ama-amino derivatives. Asetshenziswa kabanzi ekwakhiweni kwezinto eziphilayo ze-aromatic hydroxylamine kanye ne-aromatic amine, ukwelashwa kwe-tumor, ukutholwa kwezinto eziphilayo kanye nokuwohloka kokungcola kwemvelo. Kunezinhlobo ezingu-12 zemikhiqizo ye-Nitro reductase (NTR) (Inombolo njenge-ES-NTR-101~ES-NTR-112) eyenziwe yi-SyncoZymes.
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Aldolase (i-DERA)
I-ES-DERA: Ingavuselela ngempumelelo ukwengezwa kwama-ketone anikelayo kuma-receptor aldehydes. Ngaphezu kwalokho, ukusabela kungenziwa ngesisombululo samanzi se-pH engathathi hlangothi ngaphandle kwezinyathelo ezikhethekile zokuvikela. Zingaphansi kwe-aldolase yekilasi I, eyakha isisekelo se-Shiff enqubweni yokuvuselela. I-substrate ihlanganiswe ndawonye neqembu lama-amino lendawo esebenzayo ukuqala ukuphuka nokwakheka kwesibopho. Umehluko phakathi kwama-DERA namanye ama-aldolase ukuthi ama-substrate abavuselelayo angama-aldehydes futhi angadlula ekuvundeni okuqhubekayo kwama-aldehydes.
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Cytochrome P450 monooxygenase (CYP)
Mayelana ne-CYP
Ama-ES-CYP: Uhlobo lwama-enzyme e-redox ane-mercaptan-heme njengesikhungo esisebenzayo sokuvuselela ukudluliselwa komoya-mpilo. Angama-oxygenase agcinayo futhi adinga i-heme ukuze asebenze umoya-mpilo.
I-Cytochrome P450 monooxygenase ivuselela ukujiya, i-epoxidation kanye ne-hydroxylation ye-alkyl, i-hydroxylation kanye ne-oxidation ye-ammonia, i-oxidation yesulfure, i-dealkylation (i-oxygen, i-sulfur, i-ammonia), i-oxidative dehydrogenation, i-deamination kanye ne-dehalogenation.
Kunezinhlobo ezingu-8 zemikhiqizo ye-cytochrome P450 monooxygenase (Inombolo njenge-ES-CYP-101～ES-CYP-108) eyenziwe yi-SyncoZymes.Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-oxidase yotshwala (AOX)
Mayelana ne-oxidase yotshwala
Ama-ES-AOX: Lawa ma-enzyme ayakwazi ukuvuselela ukungcoliswa kwama-alcohol anamafutha noma ama-aryl-alcohol ukuze akhe ama-aldehydes. Asebenzisa i-oxygen yama-molecule kodwa awadingi i-cofactor eyengeziwe yangaphandle, kanye ne-hydrogen peroxide ekhiqizwayo.
Kunezinhlobo eziyisithupha zemikhiqizo ye-alcohol oxidases (Inombolo njenge-ES-AOX-101~ES-AOX-106) eyathuthukiswa yi-SyncoZymes. I-ES-AOX101 kanye ne-ES-AOX102 zikhetha ama-substrate e-alcohol aliphatic, i-ES-AOX103~ ES-AOX105 zikhetha ama-substrate e-alcohol anuka kamnandi, kanti i-ES-AOX106 iyi-cholesterol oxidase. I-SZ-AOX iyithuluzi eliwusizo lokuvuselela ukushiswa kwama-alcohol anamafutha noma ama-aryl-alcohols ukukhiqiza ama-aldehydes.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-D-Amino acid dehydrogenase (D-AADH)
Mayelana ne-D-Amino acid dehydrogenase
I-ES-D-AADH (i-D-Amino acid dehydrogenase): i-enzyme enganciphisa i-2-keto acid ibe yi-D-amino acid ehambisanayo. Ukusabela kudinga i-NADP(H) kanye ne-inorganic ammonia donor (njenge-ammonia noma i-ammonium ion). Kunezinhlobo ezingu-17 ze-D-amino acid dehydrogenases (Inombolo njenge-ES-DAADH-101~ ES-DAADH-117) ezakhiwe yi-SyncoZymes.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Esterase ne-Lipase (PLE ne-CALB)
Mayelana ne-Esterase ne-Lipase
Ama-ES-PLE: Uhlobo lwama-hydrolase akhuthaza ukwakheka nokuqhekeka kwama-ester bond. Angaba yingxenye yezinhlobo eziningi zokusabela kwamakhemikhali, njengokwenziwa kwe-ester, ukuguqulwa kwe-ester kanye ne-hydrolysis. Asetshenziswa kabanzi emikhakheni eminingi efana nokucubungula ukudla, imboni yamakhemikhali, i-biomedicine, imithi ye-chiral kanye nokwelashwa kwemvelo.
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Epoxide hydrolase (EH)
Mayelana ne-epoxide hydrolase
I-EH yi-ether hydrolase evuselela i-stereoselective hydrolysis yama-epoxide e-racemic ukukhiqiza ama-epoxide angu-1, 2-diol kanye nama-epoxide asebenzayo, angasetshenziswa ekuxazululeni ama-epoxide e-chiral noma ekulungiseleleni ama-diols e-chiral. Asetshenziswa kabanzi kwezokwelapha nakweminye imikhakha. Kunezinhlobo ezintathu zemikhiqizo yama-epoxide hydrolases (Inombolo njenge-ES-EH-101～ES-EH-103) eyathuthukiswa yi-SyncoZymes. I-ES-EH iyithuluzi eliwusizo lokuvuselela ukwenziwa kwama-alcohols e-chiral ngokusebenzisa i-stereoselective hydrolysis yama-epoxide e-aliphatic ne-aromatic.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Formate dehydrogenase (FDH)
Mayelana ne-Formate dehydrogenase
I-ES-FDH (i-Formate dehydrogenase): I-FDH ivuselela ukukhishwa kwe-ammonium formate ukuze ikhiqize i-carbon dioxide ne-ammonia, futhi yehlise i-NAD ibe yi-NADH nge-NAD njenge-electron receptor. I-FDH ivame ukusetshenziselwa ukuvuselelwa kwe-coenzyme NADH. Kunezinhlobo ezine zemikhiqizo ye-enzyme ye-FDH (ES-FDH-101~ES-FDH-104) eyenziwe yi-SyncoZymes, phakathi kwayo i-ES-FDH102 enomsebenzi ophezulu kakhulu futhi iyi-FDH enconywa kakhulu.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-glucose dehydrogenase (GDH)
Mayelana ne-Glucose dehydrogenase
I-ES-GDH (i-glucose dehydrogenase): I-GDH ivuselela ukukhishwa kwe-glucose ukuze ikhiqize i-gluconic acid (i-lactone), futhi yehlise i-NAD(P)+ ibe yi-NAD(P)H, nge-NAD(P)+ njenge-electron receptor. I-GDH ivame ukusetshenziselwa ukuvuselelwa kwe-coenzyme NAD(P)H emikhakheni ye-biocatalysis nezinye i-enzyme eyinhloko. Kunezinhlobo eziyi-10 zemikhiqizo ye-enzyme ye-GDH (ES-GDH-101~ES-GDH-110) eyenziwe yi-SyncoZymes, phakathi kwazo i-ES-GDH110 enomsebenzi ophezulu kakhulu futhi iyi-GDH enconywe kakhulu.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Monoamine oxidase (MAO)
Mayelana ne-Monoamine oxidase
I-ES-MAO (i-Monoamine oxidase): I-MAO ivuselela ukususwa kwe-oxidative kwama-monoamine ukuze kukhiqizwe i-hydrogen peroxide, i-ammonia kanye nama-aldehydes ahambisanayo. Enqubweni yokuvuselela, i-oxygen iyadingeka njenge-oxidant. Kunezinhlobo eziyisithupha zemikhiqizo ye-enzyme ye-MAO (Inombolo njenge-ES-MAO-101～ES-MAO-106) eyenziwe yi-SyncoZymes, engasetshenziswa ekususweni kwe-oxidative kwama-compounds e-monoamine.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Lactate Dehydrogenase (LDH)
Mayelana ne-Lactate dehydrogenase
Kukhona uhlobo olulodwa lomkhiqizo we-enzyme ye-LDH (Inombolo njenge-ES-LDH) eyakhiwe yi-SyncoZymes. I-LDH ingakhuthaza ukwehla kwe-pyruvate ibe yi-L-lactic acid, noma ukwehla kwamanye ama-α-keto acid afanayo. Enkambisweni ye-catalysis, i-NADH iyadingeka njengomthuthi we-hydrogen.
Uhlobo lokusabela kwe-catalytic lwe-lactate dehydrogenase
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
