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I-Imine reductase (IRED)
Mayelana ne-Imine reductase
I-ES-IRED: Uhlobo lwama-enzyme akhuthaza ukwehla kwesibopho se-C=N kusibopho se-CN. Lungokwe-enzyme ye-redox, ene-coenzyme NADPH yokuthutha i-hydrogen. Ngokwezintandokazi ze-chiral zemikhiqizo, zingahlukaniswa zibe yi-R-IRED kanye ne-S-IRED. Ama-Syncozymes athuthukise ama-imine reductases angu-15 (i-numbIRED ES-IRED-101-ES-IRED-115), angasetshenziswa kabanzi ekunciphiseni ama-imine ngokukhetha kanye nokukhetha ama-stereo ukuze kulungiselelwe ama-chiral amine.
Uhlobo lokusabela kwe-Catalytic:
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I-Nitrile reductase (NRED)
Mayelana ne-Nitrile reductase
Kunezinhlobo ezintathu zomkhiqizo we-enzyme ye-NRED (Inombolo njenge-ES-NRED101~ ES-NRED103) eyathuthukiswa yi-SyncoZymes. I-NRED ingakhuthaza ukwehla kweqembu le-nitrile libe yi-amine. Enkambisweni ye-catalysis, i-NADPH iyadingeka njengomthuthi we-hydrogen.
Uhlobo lokusabela lwe-Nitrile reductasecatalytic
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I-imeyili:lchen@syncozymes.com
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I-Leucine Dehydrogenase (LeuDH)
Mayelana ne-Leucine dehydrogenase
Kukhona uhlobo olulodwa lomkhiqizo we-enzyme ye-LeuDH (Inombolo njenge-ES-LeuDH-101) eyakhiwa yi-SyncoZymes. I-LeuDH ingavuselela i-ammoniation enciphisa i-4-methylbutanoic acid (usawoti) ibe yi-L-leucine noma i-oxidation ye-leucine ibe yi-4-methylbutanoic acid. I-ES-LeuDH ingavuselela futhi i-amination enciphisa i-α-keto acid enesakhiwo esifanayo ukulungiselela ama-amino acid derivatives ahambisanayo. Enkambisweni ye-catalysis, i-NADH iyadingeka njengomthuthi we-hydrogen.
Uhlobo lokusabela kwe-Leucine dehydrogenase
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I-imeyili:lchen@syncozymes.com
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I-Threonine deaminase (TDA)
Mayelana ne-Threonine deaminase
I-ES-TDA (i-Threonine deaminase): iphrotheni ye-pyridoxal phosphate evuselela ukususwa kwe-threonine ukuze ikhiqize i-2-ketobutyric acid kanye ne-ammonia. I-Pyridoxal 5-phosphate iyadingeka njenge-coenzyme ohlelweni lwe-catalytic. Kukhona uhlobo olulodwa kuphela lomkhiqizo we-enzyme ye-TDA (Inombolo njenge-ES-TDA) eyakhiwa yi-SyncoZymes, engasetshenziswa ukulungiselela i-2-ketobutyric acid noma izinto eziphuma kuyo ezivela ku-threonine.
Uhlobo lokusabela kwe-Catalytic:
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I-imeyili:lchen@syncozymes.com
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I-Amine Dehydrogenase (AmDH)
Mayelana ne-Amine Dehydrogenase
I-ES-AmDH (i-Amine Dehydrogenase): i-enzyme engakwazi ukuvuselela i-ammoniation yeqembu le-carbonyl futhi iyinciphise ibe yiqembu lama-amino. Iyi-enzyme encike ku-coenzyme NADH, futhi i-NADH isebenza njengomthumeli we-hydrogen. Kunezinhlobo ezine zemikhiqizo ye-enzyme ye-AmDH (Inombolo njenge-ES-AmDH101 ~ ES-AmDH104) eyenziwe yi-SyncoZymes, engasetshenziswa ekuhlanganiseni ama-aldehydes nama-ketone ngokukhetha kabusha noma ngokukhetha kabusha.
Uhlobo lokusabela kwe-Catalytic:
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I-imeyili:lchen@syncozymes.com
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I-Nucloside phosphorylse (NP)
Mayelana ne-nucleoside phosphorylse
Kunezinhlobo ezintathu zemikhiqizo ye-enzyme ye-NP (Inombolo njenge-ES-NP-101~ ES-NP-103) eyathuthukiswa yi-SyncoZymes. I-ES-NP-101 yi-purine nucleoside phosphorylase, i-ES-NP-102 kanye ne-ES-NP-103 yi-pyrimidine nucleoside phosphorylase. I-Nucleosidephosphorylase ingahlukanisa ama-nucleoside abe yizisekelo kanye ne-pentose phosphate. I-Nucleoside phosphorylase ingahlukaniswa ibe yi-purine nucleoside phosphorylase kanye ne-pyrimidine nucleoside phosphorylase ngokuya ngokuthanda kwezisekelo ze-nucleoside. I-purine nucleoside phosphorylase ingaguqula i-adenosine ibe yi-adenine, i-inosine ibe yi-hypoxanthine, i-guanosine ibe yi-guanine, futhi ikhiqize i-ribose phosphate ngesikhathi esifanayo. I-Pyrimidine nucleoside phosphorylase ingaguqula i-uridine ibe yi-uracil futhi ikhiqize i-ribose phosphate.
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I-Hydroaminase (HAM)
Mayelana ne-Hydroaminase
Kunezinhlobo ezimbili zomkhiqizo we-enzyme ye-HAM (Inombolo njenge-ES-HAM-101~ ES-HAM-102) eyathuthukiswa yi-SyncoZymes. I-HAM ingavuselela i-ammonia ye-enoic acid noma izinto eziphuma kuyo ukuze ikhiqize ama-amino acid e-chiral. I-HAM ingasetshenziswa ukuhlanganisa ama-amino acid e-chiral (noma ama-chiral amines) avela kuma-enoic acid (noma ama-alkenes). Umnikeli we-ammonia, njengamanzi e-ammonia noma usawoti we-ammonium, uyadingeka.
Uhlobo lokusabela kwe-Hydroaminase catalytic
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I-CALB Engashukumi
I-CALB
I-Recombinant Lipase B evela ku-Candida antarctica (CALB) ikhiqizwa ngokubiliswa okucwiliswe emanzini nge-Pichia pastoris eguquliwe ngokwezakhi zofuzo.
I-CALB ingasetshenziswa esigabeni samanzi noma esigabeni se-organic catalytic esterification, i-esterosis, i-transesterification, i-ring opening polyester synthesis, i-aminolysis, i-hydrolysis yama-amides, i-acylation yama-amine kanye nokusabela kokwengeza.
I-CALB inokukhetha okuphezulu kwe-chiral kanye nokukhetha kwesikhundla, ngakho-ke ingasetshenziswa kabanzi ekucubungulweni kwamafutha, ekudleni, emithini, ezimonyweni nakwezinye izimboni zamakhemikhali.
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I-imeyili:lchen@syncozymes.com
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I-NADH oxidase (NOX)
Mayelana ne-NADH oxidase
I-ES-NOX (i-NADH oxidase): I-NOX ivuselela ukushiswa kwe-NADH ibe yi-NAD+, futhi ingeye-oxidoreductase. Enkambisweni yokushiswa, i-O2 iyadingeka njenge-oxidant, futhi yehliswa ibe yi-H2O noma i-H2O2. Kunezinhlobo ezine zemikhiqizo ye-enzyme ye-NOX (ES-NOX-101~ES-NOX-104) eyenziwe yinkampani yethu, engasetshenziswa ekuvuseleleni ukushiswa kwe-coenzyme NAD+.
Uhlobo lokusabela kwe-Catalytic:
or
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I-imeyili:lchen@syncozymes.com
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I-Phenylalanine ammonia lyase (PAL)
Mayelana ne-Phenylalanine ammonia lyase
I-ES-PAL: Uhlobo lwama-enzyme avuselela ukuqedwa okuqondile kwe-L-phenylalanine kube yi-transcinnamic acid. Ama-Syncozymes athuthukise izinto eziyi-10 ze-phenylalanine ammonia lyase (ezinenombolo ye-ES-PAL-101~ES-PAL-110), ezingasetshenziswa ekuqedweni noma ekuphenduleni okuphambene kwe-phenylalanine kanye nezinto eziphuma kuyo.
Uhlobo lokusabela kwe-Catalytic:
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I-Catalase (i-CAT)
Mayelana ne-Catalase
I-ES-CAT (i-Catalase): ivuselela ukubola kwe-H2O2 ibe umoya-mpilo namanzi. Itholakala kakhulu kuma-mitochondria, endoplasmic reticulum, esibindini sezilwane kanye namangqamuzana egazi abomvu, ikakhulukazi esibindini lapho kugxilwe kakhulu, ihlinzeka ngomsebenzi wokuvikela umzimba nge-antioxidant. Ku-biocatalysis, isetshenziswa kakhulu ukususa i-hydrogen peroxide yomkhiqizo osabelayo kanye nokunciphisa ukuvinjelwa kanye nokungasebenzi kwe-enzyme yi-hydrogen peroxide. Kukhona uhlobo olulodwa kuphela lwemikhiqizo ye-enzyme ye-CAT eyenziwe yi-SyncoZymes (Inombolo njenge-ES-CAT).
Uhlobo lokusabela kwe-Catalytic:
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I-imeyili:lchen@syncozymes.com
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I-Lysine oxidase (LO)
Mayelana ne-Lysine oxidase
I-ES-LO (i-Lysine oxidase): ivuselela ukukhiqizwa kwe-L-lysine ibe yi-6-amino-2-oxohexanoic acid (noma i-lactone yayo). Kukhona uhlobo olulodwa kuphela lomkhiqizo we-enzyme ye-LO (Inombolo njenge-ES-LO) eyathuthukiswa yi-SyncoZymes.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
