I-Oxynitrilases (HNL)

Incazelo emfushane:

Mayelana ne-oxynitrilases

ES-HNLs: I-enzyme yekilasi eyenza ngokuzenzakalelayo ukungezwa kwe-HCN kuma-aldehydes (ketones) ukuze kutholwe u-R noma u-S ohlobo lwe-cyanide alcohols, olungaguqulelwa kalula lube izinhlobo eziningi zezidakamizwa noma izidakamizwa eziphakathi ngendlela yamakhemikhali.
Kunezinhlobo ezingama-29 zemikhiqizo ye-oxynitrilase (Inombolo njengokuthi ES-HNL-101～ES-HNL-129) ethuthukiswe yi-SyncoZymes.I-SZ-HNL iyithuluzi eliwusizo ku-regio- kanye ne-stereo- selective synthesis ye- (R) -cyanohydrins noma (S) -cyanohydrins evela ezinhlobonhlobo zama-aldehydes anuka, aliphatic kanye ne-heterocyclic noma ngisho nama-ketone.
Uhlobo lokusabela kwe-Catalytic:

I-Oxynitrilases HNL2

Iselula/Wechat/WhatsApp: +86-13681683526

I-imeyili:lchen@syncozymes.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ulwazi Lomkhiqizo:

Ama-enzyme	Ikhodi Yomkhiqizo	Ukucaciswa
I-Enzyme Powder	ES-HNL-101~ ES-HNL-129	isethi 29 oxynitrilases, 50 mg ngayinye 29 izinto * 50mg / into, noma omunye ubuningi
Ikhithi Yokuhlola (SynKit)	ES-HNL-1800	isethi 18 (S) -oxynitrilases, 1 mg ngayinye 18 izinto * 1mg / into
Ikhithi Yokuhlola (SynKit)	ES-HNL-1100	isethi 11 (R) -oxynitrilases, 1 mg ngayinye 11items * 1mg / into

Izinzuzo:

★ Ukucaciswa okuphezulu kwe-substrate.
★ Ukukhetha okuqinile kwe-chiral.
★ ukuguqulwa okuphezulu.
★ Imikhiqizo engaphansi.
★ Izimo zokusabela ezithambile.
★ Ayinandaba nemvelo.

Imiyalo yokusebenzisa:

➢ Ngokuvamile, isistimu yokusabela kufanele ifake i-substrate (aldehydes / ketones, HCN), isixazululo se-buffer (i-pH yokusabela kahle) kanye nama-enzyme.
➢ Wonke ama-ES-HNL angahlolwa ngokulandelana kwawo ohlelweni lokusabela olungenhla noma nge-HNL Screening Kit (SynKit HNL).
➢ Zonke izinhlobo ze-ES-HNL ezihambisana nezimo zokusabela ezifanele kufanele zifundwe ngazodwana.
➢ I-Substrate egxilile ephezulu noma umkhiqizo onawo ungase uvimbele umsebenzi we-ES-HNL.Kodwa-ke, ukuvimbela kungakhululwa ngokungezwa kwe-batch ye-substrate.

Izibonelo Zohlelo Lokusebenza:

Isibonelo 1⁽¹⁾:

Isitoreji:

Gcina iminyaka emi-2 ngaphansi -20 ℃.

Qaphela:

Ungalokothi uthintane nezimo eziyingozi kakhulu ezifana nalezi: izinga lokushisa eliphezulu, i-pH ephezulu/ephansi kanye ne-solvent ephilayo egxilile.