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I-Transaldolase (TAL)
Mayelana ne-Transaldolase
I-ES-TAL (i-Transaldolase): ikakhulukazi ibhekisela kuma-transaldolase e-threonine, angavuselela ukusabela kokwenziwa kwama-derivatives e-β-hydroxyphenylalanine nama-derivatives e-threonine ne-benzaldehyde. I-TAL iyi-enzyme encike ku-PLP. Kukhona uhlobo olulodwa kuphela lomkhiqizo we-enzyme ye-TAL (Inombolo njenge-ES-TAL101) eyathuthukiswa yi-SyncoZymes, engasetshenziswa ukwenziwa kwe-β-hydroxyphenylalanine kanye nama-derivatives ayo.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Ketoreductase (KRED)
Mayelana ne-Ketoreductase
Ama-enzyme: Angama-catalyst ebhayoloji e-macromolecular, ama-enzyme amaningi angamaprotheni.
I-Ketoreductase: Ebizwa nangokuthi “i-Carbonyl reductase”, ama-enzyme avuselela ukusabela kwe-redox okuguqukayo phakathi kwama-aldehydes/ketones nama-alcohols, futhi adinga ama-coenzymes njenge-H transmitter njenge-NADH noma i-NADPH. Kunezinhlobo ezintathu eziyinhloko ze-KRED: Ama-Short-chain Dehydrogenase / Reductases (ama-SDR), ama-Medium-chain Dehydrogenases / Reductases (ama-MDR), kanye nama-Aldo-KetoReductases (ama-AKR). Imisebenzi yokuvuselela yalezi zintathu iyafana, kodwa isakhiwo kanye nezakhiwo zihlukile kakhulu.
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Transaminase (ATA)
Mayelana ne-transaminase
I-ATA evela ku-SyncoZymes: Kunezinhlobo ezingu-66 zemikhiqizo ye-enzyme ye-ATA (Inombolo njenge-ES-ATA-101~ES-ATA-166) eyenziwe yi-SyncoZymes. I-SZ-ATA iyithuluzi eliwusizo lokuvuselela ukwenziwa kwama-chiral amine, ama-amino acid kanye nezinto eziphuma kuwo ezivela kuma-keto acid ahlukahlukene e-aliphatic ne-aromatic, ama-aldehydes, ama-ketone nama-ketoses.
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Nitrilase (i-NIT)
Mayelana ne-Nitrilase
Ama-ES-NIT: Guqula ngqo iqembu le-cyanide libe yiqembu le-carboxyl, ukulungiselela i-carboxylic acid, esetshenziswa kabanzi kwezokwelapha, ekuvikelweni kwemvelo, embonini yamakhemikhali, ekungezeni kokudla, ezindwangu, ekukhiqizweni kwezolimo nakwezinye izinkambu.
Kunezinhlobo ezingu-40 zemikhiqizo ye-Nitrilase (NIT) (Inombolo njenge-ES-NIT-101~ES-NIT-140) eyenziwe yi-SyncoZymes. I-ES-NIT iyithuluzi eliwusizo lokuvuselela ukwenziwa kwama-chiral carboxylic acid ngokusebenzisa i-regio- kanye ne-stereoselective hydrolysis yohlu olubanzi lwama-nitrile e-aliphatic kanye ne-aromatic.Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Nitrile hydratase (NHT)
Mayelana ne-ES-NHTs
Ama-ES-NHT: uhlobo lwe-metalloenzyme, olukhetha ukumunca ama-nitrile abe yi-primary amide ehambisanayo. Asetshenziswa kabanzi hhayi kuphela ekwakhiweni kwama-amino acid, ama-amides, ama-carboxylic acid kanye ne-derivatives yawo, kodwa futhi nasekulungiseleleni izidakamizwa ze-chiral. Kunezinhlobo ezingu-24 zama-nitrile hydratases athuthukiswe yi-SyncoZymes (Inombolo njenge-ES-NHT-101～ES-NHT-124).
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Amidase (AMD)
I-AMD evela ku-SyncoZymes: Kunezinhlobo ezingu-19 zemikhiqizo ye-enzyme ye-AMD (Inombolo njenge-ES-AMD-101~ES-AMD-119) eyathuthukiswa yi-SyncoZymes. I-SZ-AMD iyithuluzi eliwusizo lokuvuselela ukwenziwa kwe-regio- kanye ne-stereoselective kwama-chiral carboxylic acid kanye nezinto eziphuma kuzo ezivela kuma-amides ahlukahlukene e-aliphatic kanye ne-aromatic.
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Ene reductase (ERED)
Mayelana ne-ene reductase
Ama-ES-ERED: Ayingxenye yomndeni wama-enzyme amadala aphuzi anciphisa ngokukhetha i-C=C kuma-α, β-unsaturated compounds anamaqembu amunca ama-electron. Asetshenziswa kabanzi ekufundweni kwezinto ezitholakala kuma-amino acid, izinto ezisebenzayo, izinto ezisetshenziswa emithini, izinongo kanye namabhulokhi e-chiral.
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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Ama-Oxynitrilase (HNL)
Mayelana nama-oxynitrilase
Ama-ES-HNL: I-enzyme yeklasi ekhuthaza ngokungeziwe ukungezwa kwe-HCN kuma-aldehydes (ama-ketone) ukuze kutholakale uhlobo lwe-R noma lwe-S lwe-cyanide alcohols, olungaguqulwa kalula lube izinhlobo eziningi zezidakamizwa noma izidakamizwa ngokusebenzisa indlela yamakhemikhali.
Kunezinhlobo ezingu-29 zemikhiqizo ye-oxynitrilase (Inombolo njenge-ES-HNL-101～ES-HNL-129) eyathuthukiswa yi-SyncoZymes. I-SZ-HNL iyithuluzi eliwusizo lokwenziwa kwe-regio- kanye ne-stereo-selective yama-(R)-cyanohydrins noma (S)-cyanohydrins avela ezinhlobonhlobo ze-aldehydes noma ngisho nama-ketone anuka kamnandi, aliphatic kanye ne-heterocyclic.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Nitro reductase (NTR)
Mayelana ne-nitro reductase
Ama-ES-NTR: Ama-flavoenzyme akhuthaza ukwehla okuncike ku-NAD(P)H kwamaqembu e-nitro kuma-compound e-nitroaromatic kanye ne-nitroheterocyclic abe yi-hydroxylamino kanye/noma ama-amino derivatives. Asetshenziswa kabanzi ekwakhiweni kwezinto eziphilayo ze-aromatic hydroxylamine kanye ne-aromatic amine, ukwelashwa kwe-tumor, ukutholwa kwezinto eziphilayo kanye nokuwohloka kokungcola kwemvelo. Kunezinhlobo ezingu-12 zemikhiqizo ye-Nitro reductase (NTR) (Inombolo njenge-ES-NTR-101~ES-NTR-112) eyenziwe yi-SyncoZymes.
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Aldolase (i-DERA)
I-ES-DERA: Ingavuselela ngempumelelo ukwengezwa kwama-ketone anikelayo kuma-receptor aldehydes. Ngaphezu kwalokho, ukusabela kungenziwa ngesisombululo samanzi se-pH engathathi hlangothi ngaphandle kwezinyathelo ezikhethekile zokuvikela. Zingaphansi kwe-aldolase yekilasi I, eyakha isisekelo se-Shiff enqubweni yokuvuselela. I-substrate ihlanganiswe ndawonye neqembu lama-amino lendawo esebenzayo ukuqala ukuphuka nokwakheka kwesibopho. Umehluko phakathi kwama-DERA namanye ama-aldolase ukuthi ama-substrate abavuselelayo angama-aldehydes futhi angadlula ekuvundeni okuqhubekayo kwama-aldehydes.
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Cytochrome P450 monooxygenase (CYP)
Mayelana ne-CYP
Ama-ES-CYP: Uhlobo lwama-enzyme e-redox ane-mercaptan-heme njengesikhungo esisebenzayo sokuvuselela ukudluliselwa komoya-mpilo. Angama-oxygenase agcinayo futhi adinga i-heme ukuze asebenze umoya-mpilo.
I-Cytochrome P450 monooxygenase ivuselela ukujiya, i-epoxidation kanye ne-hydroxylation ye-alkyl, i-hydroxylation kanye ne-oxidation ye-ammonia, i-oxidation yesulfure, i-dealkylation (i-oxygen, i-sulfur, i-ammonia), i-oxidative dehydrogenation, i-deamination kanye ne-dehalogenation.
Kunezinhlobo ezingu-8 zemikhiqizo ye-cytochrome P450 monooxygenase (Inombolo njenge-ES-CYP-101～ES-CYP-108) eyenziwe yi-SyncoZymes.Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-oxidase yotshwala (AOX)
Mayelana ne-oxidase yotshwala
Ama-ES-AOX: Lawa ma-enzyme ayakwazi ukuvuselela ukungcoliswa kwama-alcohol anamafutha noma ama-aryl-alcohol ukuze akhe ama-aldehydes. Asebenzisa i-oxygen yama-molecule kodwa awadingi i-cofactor eyengeziwe yangaphandle, kanye ne-hydrogen peroxide ekhiqizwayo.
Kunezinhlobo eziyisithupha zemikhiqizo ye-alcohol oxidases (Inombolo njenge-ES-AOX-101~ES-AOX-106) eyathuthukiswa yi-SyncoZymes. I-ES-AOX101 kanye ne-ES-AOX102 zikhetha ama-substrate e-alcohol aliphatic, i-ES-AOX103~ ES-AOX105 zikhetha ama-substrate e-alcohol anuka kamnandi, kanti i-ES-AOX106 iyi-cholesterol oxidase. I-SZ-AOX iyithuluzi eliwusizo lokuvuselela ukushiswa kwama-alcohol anamafutha noma ama-aryl-alcohols ukukhiqiza ama-aldehydes.
Uhlobo lokusabela kwe-Catalytic:
Iselula/I-Wechat/I-WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
