I-Ketoreductase (KRED)

Incazelo emfushane:

Mayelana ne-Ketoreductase

Ama-Enzymes: Ama-macromolecular biological catalysts, ama-enzyme amaningi angamaprotheni.

I-Ketoreductase: Ebizwa nangokuthi “i-Carbonyl reductase”, ama-enzyme akhanga ukusabela kwe-redox okubuyisela emuva phakathi kwe-aldehydes / ketones notshwala, futhi adinga ama-coenzymes njengesidluliseli se-H njenge-NADH noma i-NADPH.Kunezigaba ezintathu eziyinhloko ze-KRED: I-Dehydrogenase / Reductases (SDRs), i-Medium-chain Dehydrogenases / Reductases (MDRs), kanye ne-Aldo-KetoReductases (AKRs).Imisebenzi ye-catalytic yalezi zintathu ziyefana, kodwa ukwakheka nezakhiwo kuhluke kakhulu.

Iselula/Wechat/WhatsApp: +86-13681683526

I-imeyili:lchen@syncozymes.com

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Mayelana ne-Ketoreductase:

I-KRED evela ku-SyncoZymes: Kunezinhlobo ezingu-191 zemikhiqizo ye-enzyme ye-KRED (Inombolo njengokuthi ES-KRED-101~ES-KRED-291) eyakhiwe yi-SyncoZymes.I-SZ-KRED ingasetshenziswa kabanzi ekunciphiseni i-regio- kanye ne-stereoelective ye-aldehydes, i-beta-ketone esters, i-α-ketone esters nama-ketones.

Uhlobo lokusabela kwe-Catalytic:

Ulwazi Lomkhiqizo:

Ama-enzyme	Ikhodi Yomkhiqizo	Ukucaciswa
I-Enzyme powder	I-Enzyme powder	isethi ye-187 Ketoreductases, 50 mg ngayinye 187 izinto * 50mg / into, noma elinye inani
Ikhithi Yokuhlola (SynKit)	ES-KRED-18100	isethi 181 Ketoreductases, 1 mg ngayinye 181 izinto * 1mg / into

Izinzuzo:

★ Ukucaciswa okuphezulu kwe-substrate.
★ Ukukhetha okuqinile kwe-chiral.
★ High ukuguqulwa ukusebenza kahle.
★ Imikhiqizo engaphansi.
★ Izimo zokusabela ezithambile.
★ Ayinandaba nemvelo.

Imiyalo yokusebenzisa:

➢ Ukuhlolwa kwe-enzyme kufanele kwenziwe kuma-substrate athile ngenxa yokucaciswa kwe-substrate, futhi uthole i-enzyme eyenza i-substrate eqondiwe ibe nomthelela omuhle kakhulu we-catalytic.
➢ Ungalokothi uthintane nezimo ezimbi kakhulu ezifana nalezi: izinga lokushisa eliphezulu, i-pH ephezulu/ephansi kanye ne-organic solvent enokugxila okuphezulu.
➢ Ngokuvamile, isistimu yokusabela kufanele ihlanganise i-substrate, isixazululo se-buffer, ama-coenzymes(NAD(H) noma i-NADP(H)), uhlelo lokuvuselela i-coenzyme(isb i-glucose ne-glucose dehydrogenase).
➢ I-KRED kufanele yengezwe okokugcina ohlelweni lokusabela, ngemuva kokuthi i-pH nezinga lokushisa kulungiswe esimweni sokusabela.
➢ Zonke izinhlobo ze-KRED zinezimo ezihlukahlukene zokusabela kahle, ngakho ngayinye yazo kufanele iqhutshekwe ifundwe ngayodwa.