I-Aldolase (i-DERA)

Incazelo emfushane:

I-ES-DERA: Ingavuselela ngempumelelo ukwengezwa kwama-ketone anikelayo kuma-receptor aldehydes. Ngaphezu kwalokho, ukusabela kungenziwa ngesisombululo samanzi se-pH engathathi hlangothi ngaphandle kwezinyathelo ezikhethekile zokuvikela. Zingaphansi kwe-aldolase yekilasi I, eyakha isisekelo se-Shiff enqubweni yokuvuselela. I-substrate ihlanganiswe ndawonye neqembu lama-amino lendawo esebenzayo ukuqala ukuphuka nokwakheka kwesibopho. Umehluko phakathi kwama-DERA namanye ama-aldolase ukuthi ama-substrate abavuselelayo angama-aldehydes futhi angadlula ekuvundeni okuqhubekayo kwama-aldehydes.

Iselula/I-Wechat/I-WhatsApp: +86-13681683526

I-imeyili:lchen@syncozymes.com

Sithumelele i-imeyili

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Mayelana ne-Aldolase:

Kunezinhlobo ezingu-8 zemikhiqizo ye-aldolase (Inombolo njengo-ES-DERA-101 ~ ES-DERA-108) eyathuthukiswa yi-SyncoZymes. I-SZ-DERA iyithuluzi eliwusizo lokuvuselela ukwakheka kwesibopho se-carbon-carbon esikhethayo se-enantioselective, okukhiqiza izikhungo ezimbili ze-chiral ngaphansi kwezimo zokusabela okuncane.

Uhlobo lokusabela kwe-Catalytic:

Indlela yokwenza izinto nge-catalytic:

Ulwazi Lomkhiqizo:

Ama-enzyme	Ikhodi Yomkhiqizo	Imininingwane
Impuphu ye-Enzyme	I-ES-DERA-101~ I-ES-DERA-108	isethi yama-Aldolase angu-8, ama-50 mg ngalinye izinto ezingu-8 * 50mg / into, noma olunye ubuningi
Ikhithi Yokuhlola (i-SynKit)	I-ES-DERA-800	isethi yama-Aldolase angu-8, 1 mg ngayinye Izinto ezingu-8 * 1mg / into

Izinzuzo:

★ I-spectrum ebanzi ye-substrate.
★ Ukuguqulwa okuphezulu.
★ Imikhiqizo embalwa engaphansi.
★ Izimo zokusabela okuncane.
★ Inobungani nemvelo.

Imiyalelo yokusebenzisa:

➢ Ngokuvamile, uhlelo lokusabela kufanele luhlanganise i-substrate, isixazululo se-buffer (i-pH yokusabela efanele) kanye ne-ES-DERA.
➢ Zonke izinhlobo ze-ES-DERA ezihambisana nezimo ezahlukahlukene zokusabela ezifanele kufanele zifundwe ngazinye.
➢ I-ES-DERA kufanele ifakwe ekugcineni ohlelweni lokusabela ukuze kulondolozwe umsebenzi.
➢ I-substrate eningi noma umkhiqizo one-concentration ephezulu ungavimbela umsebenzi we-ES-DERA. Kodwa-ke, ukuvinjelwa kungancishiswa ngokufaka i-substrate ngenqwaba.

Izibonelo Zokusetshenziswa:

Isibonelo 1⁽¹⁾:

Isitoreji:

Gcina iminyaka emibili ngaphansi kuka -20℃.

Ukunakwa:

Ungalokothi uthinte izimo ezimbi kakhulu ezifana nalezi: izinga lokushisa eliphezulu, i-pH ephezulu/ephansi kanye nesinyibilikisi se-organic esinomthamo ophezulu.