SyncoZymes

imikhiqizo

I-Phenylalanine dehydrogenase (PDH)

Incazelo emfushane:

Mayelana ne-Phenylalanine dehydrogenase

ES-PDH: Ikilasi le-oxidoreductase.Ukusabela okuhle kungadala ukuchithwa kwe-oxidative kasawoti we-L phenylalanine phambi kwe-NAD ukuze kukhiqizwe usawoti we-phenylpyruvate, futhi ukusabela okuphambene kungase kubangele ukuhlanganiswa kosawoti we-amino acid ohambelana nosawoti we-phenylpyruvate.Ama-syncozyme athuthukise izinto eziyi-8 ze-phenylalanine dehydrogenase (ezinezinombolo ES-PDH-101~ES-PDH-108).I-ES-PDH ingasetshenziselwa ukulungisa usawoti we-phenylalanine noma usawoti we-amino acid ohambisanayo ovela kusawoti we-phenylpyruvic acid noma okuphuma kokunye.
Uhlobo lokusabela kwe-Catalytic:

I-PDH2

Iselula/Wechat/WhatsApp: +86-13681683526

I-imeyili:lchen@syncozymes.com


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ulwazi Lomkhiqizo:

I-PDH
Ama-enzyme Ikhodi Yomkhiqizo Ukucaciswa
I-Enzyme Powder ES-PDH-101~ ES-PDH-108 isethi ye-8 Nitrile Reductase, 50 mg ngayinye 8 izinto * 50mg / into, noma elinye inani

Izinzuzo:

★ Ukucaciswa okuphezulu kwe-substrate.
★ Ukukhetha okuqinile kwe-chiral.
★ ukuguqulwa okuphezulu.
★ Imikhiqizo engaphansi.
★ Izimo zokusabela ezithambile.
★ Ayinandaba nemvelo.

Imiyalo yokusebenzisa:

➢ Ngokuvamile, isistimu yokusabela kufanele ihlanganise i-substrate, isixazululo se-buffer, i-enzyme, i-coenzyme (NAD(H)), uhlelo lokuvuselela i-coenzyme (isb. i-ammonium formate ne-formate dehydrogenase).
➢ Uhlobo ngalunye lwe-ES-PDH oluhambisana nezimo ezihlukahlukene zokusabela, ezingafundwa ngazinye uma kudingeka.
➢ I-ES-PDH kufanele yengezwe okokugcina ohlelweni lokusabela ukuze kugcinwe umsebenzi.

Izibonelo Zohlelo Lokusebenza:

Isibonelo 1(I-Biosynthesis ye-phenylalanine derivatives esuka kokuphuma kokunye kwe-phenylpyruvate)(1):

I-PDH3

Isitoreji:

Gcina iminyaka emi-2 ngaphansi -20 ℃.

Qaphela:

Ungalokothi uthintane nezimo eziyingozi kakhulu ezifana nalezi: izinga lokushisa eliphezulu, i-pH ephezulu/ephansi kanye ne-solvent ephilayo egxilile.

Izithenjwa:

1. UFrancesca Paradisi, uStuart Collins, et al.Ijenali ye-Biotechnology, 2007, 128, 408–411.


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