Isithombe Esifakiwe se-Phenylalanine dehydrogenase (PDH)

I-Phenylalanine dehydrogenase (PDH)

Incazelo emfushane:

Mayelana ne-Phenylalanine dehydrogenase

I-ES-PDH: Uhlobo lwe-oxidoreductase. Ukusabela okuhle kungavuselela ukususwa kwe-oxidative kwe-L phenylalanine salt lapho kukhona i-NAD ukuze kukhiqizwe usawoti we-phenylpyruvate, kanti ukusabela okuphambene nakho kungavuselela ukwenziwa kwe-amino acid salt ehambisanayo kusuka kusawoti we-phenylpyruvate. Ama-Syncozymes athuthukise izinto ezingu-8 ze-phenylalanine dehydrogenase (ezinenombolo ze-ES-PDH-101~ES-PDH-108). I-ES-PDH ingasetshenziswa ukulungiselela usawoti we-phenylalanine noma usawoti we-amino acid ohambisanayo kusuka kusawoti we-phenylpyruvic acid noma ama-derivatives.
Uhlobo lokusabela kwe-Catalytic:

I-PDH2

Iselula/I-Wechat/I-WhatsApp: +86-13681683526

I-imeyili:lchen@syncozymes.com

Sithumelele i-imeyili

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ulwazi Lomkhiqizo:

Ama-enzyme	Ikhodi Yomkhiqizo	Imininingwane
Impuphu ye-Enzyme	I-ES-PDH-101~ I-ES-PDH-108	isethi ye-8 Nitrile Reductase, 50 mg ngayinye izinto ezingu-8 * 50mg / into, noma olunye ubuningi

Izinzuzo:

★ Ukucaciswa okuphezulu kwe-substrate.
★ Ukukhetha okunamandla kwe-chiral.
★ Ukuguqulwa okuphezulu.
★ Imikhiqizo embalwa engaphansi.
★ Izimo zokusabela okuncane.
★ Inobungani nemvelo.

Imiyalelo yokusebenzisa:

➢ Ngokuvamile, uhlelo lokusabela kufanele luhlanganise i-substrate, isixazululo se-buffer, i-enzyme, i-coenzyme (NAD(H)), uhlelo lokuvuselela i-coenzyme (isb. i-ammonium formate kanye ne-formate dehydrogenase).
➢ Uhlobo ngalunye lwe-ES-PDH luhambisana nezimo ezahlukahlukene zokusabela ezifanele, ezingafundwa ngazinye uma kudingeka.
➢ I-ES-PDH kufanele ifakwe ekugcineni ohlelweni lokusabela ukuze kulondolozwe umsebenzi.

Izibonelo Zokusetshenziswa:

Isibonelo 1 (Ukwenziwa kwezinto eziphuma ku-phenylalanine ezivela ku-phenylpyruvate derivatives)⁽¹⁾:

Isitoreji:

Gcina iminyaka emibili ngaphansi kuka -20℃.

Ukunakwa:

Ungalokothi uthinte izimo ezimbi kakhulu ezifana nalezi: izinga lokushisa eliphezulu, i-pH ephezulu/ephansi kanye nesinyibilikisi se-organic esinomthamo ophezulu.