I-Cyclooxygenase (COX)

Incazelo emfushane:

Mayelana ne-Cyclooxygenase

I-ES-COX (i-Cyclooxygenase): igqugquzela ukuguqulwa kwamabhondi e-C=C abe yi-epoxide.Kunezinhlobo ezingu-11 zemikhiqizo ye-enzyme ye-COX (Inombolo njenge-ES-COX101~ ES-COX-111) eyakhiwe yi-SyncoZymes.Ngokuya ngendlela ehlukile ye-catalytic, i-COX ye-SyncoZymes ihlukaniswe yaba i-haloperoxidase ne-styrene monooxygenase.I-ES-COX101, 102, 107-111 ingeye-haloperoxidase, kuyilapho i-ES-COX103-106 ingeye-styrene monooxygenase.

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I-imeyili:lchen@syncozymes.com

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Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Mayelana ne-Cyclooxygenase:

Uhlobo lokusabela kwe-Catalytic:

I-Haloperoxidase:

I-Styrene monooxygenase:

Ulwazi Lomkhiqizo:

Ama-enzyme	Ikhodi Yomkhiqizo	Ukucaciswa
I-Enzyme powder	ES-COX-101~ ES-COX-110	isethi ye-10 NADH Cyclooxygenase, 50 mg into ngayinye 10 izinto * 50mg / into, noma elinye inani

Izinzuzo:

★ Ukucaciswa okuphezulu kwe-substrate.
★ Ukukhetha okuqinile kwe-chiral.
★ ukuguqulwa okuphezulu.
★ Imikhiqizo engaphansi.
★ Izimo zokusabela ezithambile.
★ Ayinandaba nemvelo.

Imiyalo yokusebenzisa:

➢ Ngokuvamile, uhlelo lokusabela kwe-haloperoxidase luhlanganisa: i-substrate, i-buffer, i-enzyme, i-H2O2 ne-halogen ion.I-Styrene monooxygenase reaction system ihlanganisa i-substrate, i-buffer, i-enzyme, i-coenzyme kanye nesistimu yokuvuselela i-coenzyme.
➢ I-COX kufanele yengezwe okokugcina ohlelweni lokusabela, ngemuva kokuthi i-pH nezinga lokushisa kulungiswe esimweni sokusabela.

Izibonelo Zohlelo Lokusebenza:

Isibonelo 1(Ukuhlanganiswa kokuphuma kwe-epoxy styrene kokuphuma kokunye kwe-styrene)⁽¹⁾:

Qaphela: izibonelo zohlelo lokusebenza nezinkomba zihloselwe ukukhombisa ububanzi bohlelo lwe-COX ukuze kube lula ukuqonda, futhi azihambisani ne-enzyme ethile ye-SyncoZymes.

Isitoreji:

Gcina iminyaka emi-2 ngaphansi -20 ℃.

Qaphela:

Ungalokothi uthintane nezimo eziyingozi kakhulu ezifana nalezi: izinga lokushisa eliphezulu, i-pH ephezulu/ephansi kanye ne-solvent ephilayo egxilile.