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I-Esterase&Lipase (PLE&CALB)
Mayelana ne-Esterase&Lipase
ES-PLEs: Ikilasi lama-hydrolases abangela ukwakheka nokuphuka kwamabhondi e-ester.Bangabamba iqhaza ezinhlotsheni eziningi zokusabela kwamakhemikhali ezinto eziphilayo, njenge-esterification, i-transesterification kanye ne-hydrolysis.Zisetshenziswa kakhulu emikhakheni eminingi efana nokucubungula ukudla, imboni yamakhemikhali, i-biomedicine, imithi ye-chiral kanye nokwelashwa kwemvelo.
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Epoxide hydrolase (EH)
Mayelana ne-epoxide hydrolase
I-EH i-ether hydrolase eyenza i-stereoelective hydrolysis yama-racemic epoxides ukukhiqiza i-1, 2-diol kanye nama-epoxide asebenzayo, angasetshenziselwa ukulungiswa kwe-chiral yama-epoxides noma ukulungiswa kwama-chiral diols.Asetshenziswa kakhulu kwezokwelapha nakweminye imikhakha.Kunezinhlobo ezi-3 zemikhiqizo ye-epoxide hydrolases (Inombolo njengokuthi ES-EH-101～ES-EH-103) ethuthukiswe yi-SyncoZymes.I-ES-EH iyithuluzi eliwusizo lokugqugquzela ukuhlanganiswa kotshwala be-chiral ngokusebenzisa i-stereoelective hydrolysis yama-aliphatic and aromatics epoxides.
Uhlobo lokusabela kwe-Catalytic:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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Yenza i-dehydrogenase (FDH)
Mayelana ne-Formate dehydrogenase
I-ES-FDH (Formate dehydrogenase): I-FDH yenza i-dehydrogenation ye-ammonium formate ikhiqize i-carbon dioxide ne-ammonia, futhi yehlise i-NAD ibe yi-NADH nge-NAD njengesamukeli sama-electron.I-FDH ivame ukusetshenziselwa ukuvuselelwa kwe-coenzyme NADH.Kunezinhlobo ezi-4 zemikhiqizo ye-enzyme ye-FDH (ES-FDH-101~ES-FDH-104) eyakhiwe yi-SyncoZymes, phakathi kwayo i-ES-FDH102 inomsebenzi ophezulu kakhulu futhi iyi-FDH enconywa kakhulu.
Uhlobo lokusabela kwe-Catalytic:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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IGlucose dehydrogenase (GDH)
Mayelana neGlucose dehydrogenase
I-ES-GDH (I-Glucose dehydrogenase): I-GDH yenza i-dehydrogenation ye-glucose ikhiqize i-gluconic acid (lactone), futhi yehlise i-NAD(P)+ ibe yi-NAD(P)H, nge-NAD(P)+ njenge-electron receptor.I-GDH ivame ukusetshenziselwa ukuvuselelwa kwe-coenzyme NAD(P)H emikhakheni ye-biocatalysis nenye i-enzyme eyinhloko.Kunezinhlobo ezingu-10 zemikhiqizo ye-enzyme ye-GDH (ES-GDH-101~ES-GDH-110) eyakhiwe yi-SyncoZymes, phakathi kwayo i-ES-GDH110 inomsebenzi ophezulu kakhulu futhi iyi-GDH enconywa kakhulu.
Uhlobo lokusabela kwe-Catalytic:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Monoamine oxidase (MAO)
Mayelana ne-Monoamine oxidase
I-ES-MAO(Monoamine oxidase): I-MAO yenza i-oxidative deamination ye-monoamines ikhiqize i-hydrogen peroxide, i-ammonia kanye nama-aldehyde ahambisanayo.Enqubweni ye-catalytic, umoya-mpilo uyadingeka njenge-oxidant.Kunezinhlobo eziyisi-6 zemikhiqizo ye-enzyme ye-MAO (Inombolo njenge-ES-MAO-101～ES-MAO-106) eyakhiwe yi-SyncoZymes, engasetshenziswa ekuqedeni i-oxidative yezinhlanganisela ze-monoamine.
Uhlobo lokusabela kwe-Catalytic:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Lactate Dehydrogenase (LDH)
Mayelana ne-Lactate dehydrogenase
Kunohlobo olungu-1 lomkhiqizo we-enzyme ye-LDH (Inombolo njenge-ES-LDH) eyakhiwe yi-SyncoZymes.I-LDH ingabangela ukuncipha kwe-pyruvate ku-L-lactic acid, noma ukunciphisa amanye ama-α-keto acid afanayo.Enqubweni ye-catalysis, i-NADH iyadingeka njengesithuthi se-hydrogen.
Uhlobo lokusabela lwe-lactate dehydrogenasecatalytic
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Imine reductase (IRED)
Mayelana ne-Imine reductase
ES-IRED: Ikilasi lama-enzyme adala ukuncipha kwesibopho se-C=N kubhondi ye-CN.Kungokwe-redox enzyme, ene-coenzyme NADPH yokuhamba nge-hydrogen.Ngokuya ngokuthandwa kwe-chiral kwemikhiqizo, ingahlukaniswa nge-R-IRED kanye ne-S-IRED.Ama-syncozymes athuthukise ama-imine reductases angu-15 (numbIRED ES-IRED-101-ES-IRED-115), angasetshenziswa kakhulu ekunciphiseni i-regioselective kanye ne-stereoselective yama-imine ukuze kulungiswe ama-chiral amines.
Uhlobo lokusabela kwe-Catalytic:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Nitrile reductase (NRED)
Mayelana ne-Nitrile reductase
Kukhona uhlobo olu-3 lomkhiqizo we-enzyme ye-NRED (Inombolo njenge-ES-NRED101~ ES-NRED103) eyakhiwe yi-SyncoZymes.I-NRED ingadala ukwehliswa kweqembu le-nitrile libe yi-amine.Enqubweni ye-catalysis, i-NADPH iyadingeka njengesithuthi se-hydrogen.
Uhlobo lokusabela lwe-Nitrile reductasecatalytic
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Phenylalanine dehydrogenase (PDH)
Mayelana ne-Phenylalanine dehydrogenase
ES-PDH: Ikilasi le-oxidoreductase.Ukusabela okuhle kungadala ukuchithwa kwe-oxidative kasawoti we-L phenylalanine phambi kwe-NAD ukuze kukhiqizwe usawoti we-phenylpyruvate, futhi ukusabela okuphambene kungase kubangele ukuhlanganiswa kosawoti we-amino acid ohambelana nosawoti we-phenylpyruvate.Ama-syncozyme athuthukise izinto eziyi-8 ze-phenylalanine dehydrogenase (ezinezinombolo ES-PDH-101~ES-PDH-108).I-ES-PDH ingasetshenziselwa ukulungisa usawoti we-phenylalanine noma usawoti we-amino acid ohambisanayo ovela kusawoti we-phenylpyruvic acid noma okuphuma kokunye.
Uhlobo lokusabela kwe-Catalytic:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Leucine Dehydrogenase (LeuDH)
Mayelana ne-Leucine dehydrogenase
Kunohlobo olungu-1 lomkhiqizo we-enzyme ye-LeuDH (Inombolo njengokuthi ES-LeuDH-101) eyakhiwe i-SyncoZymes.I-LeuDH ingakwazi ukuvuselela i-ammoniation enciphisa i-4-methylbutanoic acid (usawoti) ku-L-leucine noma i-oxidation ye-leucine ku-4-methylbutanoic acid.I-ES-LeuDH ingase futhi ibangele ukukhishwa okunciphisayo kwama-α-keto acid anesakhiwo esifanayo ukuze kulungiselelwe okuphuma kokuphuma kwe-amino acid okuhambisanayo.Enqubweni ye-catalysis, i-NADH iyadingeka njengesithuthi se-hydrogen.
Uhlobo lokusabela lwe-Leucine dehydrogenasecatalytic
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Threonine deaminase (TDA)
Mayelana ne-Threonine deaminase
I-ES-TDA (i-Threonine deaminase): iphrotheni ye-pyridoxal phosphate eyenza ukuchithwa kwe-threonine ukukhiqiza i-2-ketobutyric acid ne-ammonia.I-Pyridoxal 5-phosphate iyadingeka njenge-coenzyme ohlelweni lwe-catalytic.Kukhona uhlobo olulodwa kuphela lomkhiqizo we-enzyme ye-TDA (Inombolo njenge-ES-TDA) eyakhiwe i-SyncoZymes, engasetshenziswa ukulungisa i-2-ketobutyric acid noma okuphuma kuyo ku-threonine.
Uhlobo lokusabela kwe-Catalytic:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
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I-Amine Dehydrogenase (AmDH)
Mayelana ne-Amine Dehydrogenase
I-ES-AmDH (i-Amine Dehydrogenase): i-enzyme engakwazi ukuvuselela i-ammoniation yeqembu le-carbonyl futhi iyinciphise ibe yiqembu lama-amino.Kuyi-coenzyme encike ku-NADH, futhi i-NADH isebenza njengesidluliseli se-hydrogen.Kunezinhlobo ezi-4 zemikhiqizo ye-enzayimu ye-AmDH (Inombolo njengokuthi ES-AmDH101～ES-AmDH104) ethuthukiswe yi-SyncoZymes, engasetshenziswa ku-regioselective noma i-stereoelective reductive amination yama-aldehydes nama-ketone.
Uhlobo lokusabela kwe-Catalytic:
Iselula/Wechat/WhatsApp: +86-13681683526
I-imeyili:lchen@syncozymes.com
