SyncoZymes

imikhiqizo

I-Benzaldehyde lyase (BAL)

Incazelo emfushane:

Mayelana ne-Benzaldehyde lyase

I-ES-BAL (i-Benzaldehyde lyase): uhlobo lwe-enzyme eyenza i-hydroxymethylation ye-aldehyde enamakha ne-aliphatic ene-formaldehyde ukukhiqiza i-α-Hydroxymethyl ketone ehambisanayo.I-BAL yi-thiamine diphosphate (ThDP) - i-enzyme encike.Kunohlobo olungu-1 kuphela lomkhiqizo we-enzyme ye-BAL (Inombolo njengokuthi ES-BAL101) ethuthukiswe i-SyncoZymes, engasetshenziselwa i-hydroxymethylation ye-aldehyde enamakha ne-aliphatic.

Uhlobo lokusabela kwe-Catalytic:

I-Benzaldehyde lyase BAL

Iselula/Wechat/WhatsApp: +86-13681683526

I-imeyili:lchen@syncozymes.com


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Izinzuzo:

★ Ukucaciswa okuphezulu kwe-substrate.
★ Ukukhetha okuqinile kwe-chiral.
★ ukuguqulwa okuphezulu.
★ Imikhiqizo engaphansi.
★ Izimo zokusabela ezithambile.
★ Ayinandaba nemvelo.

Imiyalo yokusebenzisa:

➢ Ngokuvamile, isistimu yokusabela kufanele ifake i-substrate, isisombululo se-buffer, i-enzyme, i-ThDP, i-Mg2+.
➢ I-BAL kufanele yengezwe okokugcina ohlelweni lokusabela, ngemuva kokuthi i-pH nezinga lokushisa kulungiswe esimweni sokusabela.

Izibonelo Zohlelo Lokusebenza:

Isibonelo 1(Ukuhlanganiswa kwe-N-efakwe esikhundleni se-1,2 amino alcohols evela ku-aldehydes)(1):

I-Benzaldehyde lyase BA2

Isitoreji:

Gcina iminyaka emi-2 ngaphansi -20 ℃.

Qaphela:

Ungalokothi uthintane nezimo eziyingozi kakhulu ezifana nalezi: izinga lokushisa eliphezulu, i-pH ephezulu/ephansi kanye ne-solvent ephilayo egxilile.

Izithenjwa:

1. U-Li Y, u-Hu N, u-Xu Z, nabanye.I-Angewandte Chemie International Edition, 2022, 61(17): e202116344.


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