Isithombe Esifakiwe se-Oxynitrilases (HNL)

Ama-Oxynitrilase (HNL)

Incazelo emfushane:

Mayelana nama-oxynitrilase

Ama-ES-HNL: I-enzyme yeklasi ekhuthaza ngokungeziwe ukungezwa kwe-HCN kuma-aldehydes (ama-ketone) ukuze kutholakale uhlobo lwe-R noma lwe-S lwe-cyanide alcohols, olungaguqulwa kalula lube izinhlobo eziningi zezidakamizwa noma izidakamizwa ngokusebenzisa indlela yamakhemikhali.
Kunezinhlobo ezingu-29 zemikhiqizo ye-oxynitrilase (Inombolo njenge-ES-HNL-101～ES-HNL-129) eyathuthukiswa yi-SyncoZymes. I-SZ-HNL iyithuluzi eliwusizo lokwenziwa kwe-regio- kanye ne-stereo-selective yama-(R)-cyanohydrins noma (S)-cyanohydrins avela ezinhlobonhlobo ze-aldehydes noma ngisho nama-ketone anuka kamnandi, aliphatic kanye ne-heterocyclic.
Uhlobo lokusabela kwe-Catalytic:

Ama-Oxynitrilase HNL2

Iselula/I-Wechat/I-WhatsApp: +86-13681683526

I-imeyili:lchen@syncozymes.com

Sithumelele i-imeyili

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ulwazi Lomkhiqizo:

Ama-enzyme	Ikhodi Yomkhiqizo	Imininingwane
Impuphu ye-Enzyme	I-ES-HNL-101~ I-ES-HNL-129	isethi yama-oxynitrilase angu-29, 50 mg ngayinye Izinto ezingu-29 * 50mg / into, noma olunye ubuningi
Ikhithi Yokuhlola (i-SynKit)	I-ES-HNL-1800	isethi yama-oxynitrilase angu-18 (S), 1 mg ngayinye Izinto ezingu-18 * 1mg / into
Ikhithi Yokuhlola (i-SynKit)	I-ES-HNL-1100	isethi yama-oxynitrilase ayi-11 (R), 1 mg ngayinye 11items * 1mg / into

Izinzuzo:

★ Ukucaciswa okuphezulu kwe-substrate.
★ Ukukhetha okunamandla kwe-chiral.
★ Ukuguqulwa okuphezulu.
★ Imikhiqizo embalwa engaphansi.
★ Izimo zokusabela okuncane.
★ Inobungani nemvelo.

Imiyalelo yokusebenzisa:

➢ Ngokuvamile, uhlelo lokusabela kufanele luhlanganise i-substrate (ama-aldehyde / ama-ketone, i-HCN), isixazululo se-buffer (i-pH yokusabela efanele) kanye nama-enzyme.
➢ Wonke ama-ES-HNL angahlolwa ngokulandelana ohlelweni lokusabela olungenhla noma nge-HNL Screening Kit (SynKit HNL).
➢ Zonke izinhlobo ze-ES-HNL ezihambisana nezimo ezahlukahlukene zokusabela ezifanele kufanele zifundwe ngazinye.
➢ I-substrate eningi noma umkhiqizo one-concentration ephezulu ungavimbela umsebenzi we-ES-HNL. Kodwa-ke, ukuvinjelwa kungancishiswa ngokungezwa kwe-substrate ngeqembu.

Izibonelo Zokusetshenziswa:

Isibonelo 1⁽¹⁾:

Isitoreji:

Gcina iminyaka emibili ngaphansi kuka -20℃.

Ukunakwa:

Ungalokothi uthinte izimo ezimbi kakhulu ezifana nalezi: izinga lokushisa eliphezulu, i-pH ephezulu/ephansi kanye nesinyibilikisi se-organic esinomthamo ophezulu.