I-β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
I-SyncoZymes (Shanghai) Co., Ltd. ingumkhiqizi oholayo nomphakeli we-β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS:53-59-8) enekhwalithi ephezulu.Singahlinzeka nge-COA, ukulethwa komhlaba wonke, amanani amancane kanye nenqwaba etholakalayo.Uma unentshisekelo kulo mkhiqizo, sicela uthumele imininingwane enemininingwane ehlanganisa inombolo ye-CAS, igama lomkhiqizo, nenani kithi.Sicela uxhumane:lchen@syncozymes.com
| Igama Lekhemikhali | I-β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Omqondofana | I-β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Inombolo ye-CAS | 53-59-8 |
| Isisindo samangqamuzana | 743.41 |
| I-Molecular Formula | I-C21H28N7O17P3 |
| I-EINECS No. | 200-178-1 |
| izinga lokushisa lokugcina. | Gcina endaweni emnyama, emkhathini ongangeni, Gcina efrijini, ngaphansi kuka -20°C |
| ukuncibilika | I-H2O: 50 mg/mL, icacile, iphuzi kancane |
| pka | pKa1 3.9;pKa2 6.1(at 25℃) |
| λ ubuningi | 260nm(lit.) |
| I-Merck | 14,6348 |
| I-EPA Substance Registry System | I-Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), P'.fwdarw.5'-ester ne-3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, usawoti wangaphakathi (53-59- 8) |
| Into yokuhlola | Imininingwane |
| Ukubukeka | Impushana emhlophe ukuya kokuphuzi |
| Ukuncibilika | 200mg/ml emanzini |
| Inani le-pH (100mg/ml) | 5.0-7.0 |
| Ukuhlaziywa kwe-UV Spectral I-Eat 260 nm kanye ne-pH 7.5 | (18±1.0)×10³L/mol/cm |
| Okuqukethwe (ngokuhlaziywa kwe-enzymatic no-G6I-PDH ku-pH 7.5, kusetshenziswa i-spectrophotometer, i-abs.340nm, kusisekelo se-anhydrous) | ≥90.0% |
| Ukuhlanzeka (nge-HPLC, %indawo) | ≥95.0% |
| Okuqukethwe kwamanzi (nge-KF) | ≤5% |
Iphakheji:Ibhodlela, isikhwama se-Aluminium foil, 25kg/Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sesitoreji:Gcina umiswe ngokuqinile ebumnyameni, ukuze isitoreji eside sigcine ku-2~8℃.
I-NADP iyi-coenzyme, okuyindawo lapho i-nicotinamide adenine dinucleotide kanye ne-molecule ye-phosphate kuboshwe i-ester bond, futhi ikhona kabanzi.emhlabeni webhayoloji.Izici zayo zamakhemikhali, i-spectrum yokumuncwa, ifomu le-redox, njll. zifana ne-NAD (Coenzyme I).I-NADP ingasetshenziswa kabanzi ekuphenduleniIkhiqizwa ngama-dehydrogenases e-alcohol ahlukahlukene, ama-ketoreductases namanye ama-oxidoreductases.Okufana nokuthi: kungancishiswa ku-NADPH ngama-dehydrogenase amaningi anjalonjenge-6-phosphoglucose dehydrogenase (EC.1.1.1.49), 6-phosphogluconate dehydrogenase (EC.1.1.1.44).Nokho, akukwazi ngempela ukusabela kwabaningiama-dehydrogenases asebenzisa i-NAD, futhi angeke afakwe i-oxidized ngokuqondile yiketango lokuphefumula.Ngokungafani ne-NAD, itholakala ikakhulukazi esimweni esincishisiwe kumaseli wezinto eziphilayo ze-aerobic.
Ngokusetshenziswa komkhiqizo, ingahlukaniswa ngamamaki alandelayo: ibanga le-biotransformation, ibanga lokuxilonga le-reagent, ibanga lokudla kwezempilo.
Ibanga le-Biotransformation: Ingasetshenziselwa ukuhlanganiswa kwama-intermediates emithi kanye nama-API, ikakhulukazi ngama-enzyme e-catalytic, njenge-ketoreductase (KRED),I-P450 monooxygenase (CYP), i-formate dehydrogenase (FDH), i-glucose dehydrogenase (GDH), njll. Linda.
Ibanga le-Diagnostic reagent: Ngezinhlobonhlobo zama-enzyme okuxilonga, njengempahla eluhlaza yamakhithi okuxilonga.
Ibanga lokudla kwezempilo: Ukusetshenziswa kwesengezo sokudla kwe-NADP kusenqubweni yocwaningo nentuthuko.
