i-β-Nicotinamide adenine dinucleotide phosphate hydrate (NADP)
I-SyncoZymes (Shanghai) Co., Ltd. ingumkhiqizi ohamba phambili nomhlinzeki we-β-Nicotinamide adenine dinucleotide phosphate hydrate (CAS:53-59-8) ngekhwalithi ephezulu. Singanikeza i-COA, ukulethwa komhlaba wonke, inani elincane neliningi elitholakalayo. Uma unesithakazelo kulo mkhiqizo, sicela usithumelele ulwazi oluningiliziwe olufaka phakathi inombolo ye-CAS, igama lomkhiqizo, inani. Sicela uxhumane nathi:lchen@syncozymes.com
| Igama Lekhemikhali | i-β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Amagama afanayo | i-β-Nicotinamide adenine dinucleotide phosphate hydrate |
| Inombolo ye-CAS | 53-59-8 |
| Isisindo sama-molecule | 743.41 |
| Ifomula Yamamolekyuli | C21H28N7O17P3 |
| Inombolo ye-EINECS | 200-178-1 |
| izinga lokushisa lokugcina. | Gcina endaweni emnyama, emoyeni ongcolile, Gcina efrijini, ngaphansi kuka -20°C |
| ukuncibilika | I-H2O: 50 mg/mL, icacile, iphuzi kancane |
| i-pka | pKa1 3.9; pKa2 6.1(ku-25℃) |
| ubuningi be-λ | 260nm (okukhanyayo) |
| I-Merck | 14,6348 |
| Uhlelo Lokubhalisa Izidakamizwa lwe-EPA | I-Adenosine 5'-(trihydrogen diphosphate), 2'-(dihydrogen phosphate), i-P'.fwdarw.5'-ester ene-3-(aminocarbonyl)-1-.beta.-D-ribofuranosylpyridinium, usawoti wangaphakathi (53-59-8) |
| Into Yokuhlola | Imininingwane |
| Ukubukeka | Impuphu emhlophe kuya ephuzi |
| Ukuncibilika | 200mg/ml emanzini |
| Inani le-pH (100mg/ml) | 5.0～7.0 |
| Ukuhlaziywa kwe-UV Spectral ku-260 nm kanye ne-pH engu-7.5 | (18±1.0)×10³L/mol/cm |
| Okuqukethwe (ngokuhlaziywa kwe-enzyme nge-G6I-PDH ku-pH 7.5, kusetshenziswa i-spectrophotometer, i-abs.340nm, ngesisekelo se-anhydrous) | ≥90.0% |
| Ubumsulwa (nge-HPLC, %indawo) | ≥95.0% |
| Okuqukethwe kwamanzi (nge-KF) | ≤5% |
Iphakheji:Ibhodlela, isikhwama sefoyile ye-aluminium, i-25kg/i-Cardboard Drum, noma ngokwezidingo zekhasimende.
Isimo Sokugcina:Gcina ivalwe ngokuqinile ebumnyameni, ukuze igcinwe isikhathi eside, gcina ku-2 ~ 8℃.
I-NADP iyi-coenzyme, okuyinto lapho i-nicotinamide adenine dinucleotide kanye ne-molecule ye-phosphate ziboshwe khona yisibopho se-ester, futhi zikhona kabanziemhlabeni wezinto eziphilayo. Izakhiwo zayo zamakhemikhali, ububanzi bokumuncwa, isimo se-redox, njll. zifana ne-NAD (Coenzyme I). I-NADP ingasetshenziswa kabanzi ekuphenduleniiqhutshwa yi-alcohol dehydrogenases ehlukahlukene, ama-ketoreductases kanye namanye ama-oxidoreductases. Njenge: ingancishiswa ibe yi-NADPH yi-dehydrogenases eziningi ezifananjenge-6-phosphoglucose dehydrogenase (EC.1.1.1.49), i-6-phosphogluconate dehydrogenase (EC.1.1.1.44). Kodwa-ke, ayikwazi ngempela ukusabela kwabaningiama-dehydrogenase asebenzisa i-NAD, futhi awakwazi ukungcoliswa ngqo yi-respiration chain. Ngokungafani ne-NAD, ikhona ikakhulukazi esimweni esinciphile kumaseli ezinto eziphilayo ze-aerobic.
Ngokusho kokusetshenziswa komkhiqizo, ungahlukaniswa ngamamaki alandelayo: ibanga le-biotransformation, ibanga le-diagnostic reagent, ibanga lokudla okunempilo.
Izinga lokuguqulwa kwe-Bio: Lingasetshenziswa ekuhlanganiseni izinto ezisetshenziswa kwezokwelapha kanye nama-API, ikakhulukazi ngama-enzyme e-catalytic, njenge-ketoreductase (KRED),I-P450 monooxygenase (CYP), i-formate dehydrogenase (FDH), i-glucose dehydrogenase (GDH), njll. Linda.
Ibanga le-reagent yokuxilonga: Linama-enzyme ahlukahlukene okuxilonga, njengezinto zokusetshenziswa zamakhithi okuxilonga.
Izinga lokudla okunempilo: Ukusetshenziswa kwe-NADP kwesengezo sokudla ikakhulukazi kusenqubo yocwaningo nentuthuko.
