I-Triglyceride (TG) uhlobo lwamafutha anokuqukethwe okukhulu emzimbeni womuntu.Zonke izitho nezicubu zomzimba womuntu zingasebenzisa i-triglyceride ukunikeza amandla, futhi isibindi singahlanganisa i-triglyceride futhi siyigcine esibindini.Uma i-triglyceride inyuswa, kusho ukuthi isibindi siqoqa amafutha amaningi, okuyisibindi esinamafutha.I-Triglyceride iwuhlobo lwe-hyperlipidemia, futhi umonakalo wayo omkhulu emzimbeni womuntu ukubangela i-atherosclerosis, ukuvinjelwa kwemithambo yegazi kanye ne-thrombosis.Ngaphezu kwalokho, ucwaningo luye lwabonisa ukuthi i-triglycerides ephezulu ingabangela nomfutho wegazi ophezulu, i-gallstones, i-pancreatitis, isifo se-Alzheimer nokunye.
Ucwaningo lwakamuva lomtholampilo wabantu eJapan luphinde lwafakazela izinzuzo ze-NMN emzimbeni womuntu.Ngokuhlolwa komtholampilo kwabantu, ithimba labacwaningi likufakazele ukuthi umjovo womjovo we-NMN uphephile emzimbeni womuntu, ongakwazi nje ukukhulisa kakhulu izinga le-NAD+ legazi, kodwa futhi wehlise kakhulu izinga le-triglyceride yegazi ngaphandle kokulimaza amaseli egazi.
Ithimba labacwaningi liqashe amavolontiya anempilo ayi-10 (abesilisa aba-5 nabesifazane abangu-5, abaneminyaka engama-20 ukuya kwengama-70).Ngemva kokuzila ukudla amahora angu-12, i-300mg ye-NMN yachithwa ku-100mL saline futhi yajova kumavolontiya ngomthambo wengalo (5mL/min).I-X-ray yesifuba yathathwa ngaphambi nangemva kokujova kwe-NMN, futhi isisindo, izinga lokushisa, umfutho wegazi, i-pulse kanye ne-blood saturation saturation kwalinganiswa.Igazi nomchamo kwaqoqwa ukuze kuhlolwe.Ngokuhlaziya okuqhathaniswayo kwenani lemiphumela yokuhlolwa, kutholakala ukuthi izimpawu eziyinhloko zesibindi, amanyikwe, inhliziyo nezinso azikho izinguquko ezisobala, futhi ngaphezu kwalokho, ngeke zithinte izimpawu eziyinhloko zamangqamuzana egazi abomvu, amangqamuzana amhlophe egazi. namaplatelet egazini, futhi ababambiqhaza abanakho ukusabela okubi.
Kuyaqapheleka ukuthi izinga le-triglyceride egazini selishintshile ngokusobala.Ngemuva kokuthi izihloko zithole umjovo we-NMN isigamu sehora, izinga le-triglyceride lehla ngokusobala, kuze kube amahora angu-5 kamuva, nakuba kwakukhona umkhuba omncane wokubuyisela, lo mehluko obalulekile wawusekhona.
Kusukela ekuhlolweni kwezilwane zangaphambi komtholampilo kuya ekuhlolweni komtholampilo kwabantu, izinzuzo ze-NMN emzimbeni womuntu ziqinisekiswe ngempumelelo.Lolu cwaningo lomtholampilo womuntu lufakazela umsebenzi we-NMN ekwehliseni i-triglyceride, okuyizindaba ezinhle kubantu abakhuluphele nasebekhulile.
Izithenjwa:
[1].Kimura S, Ichikawa M, Sugawara S, et al.(Septhemba 05, 2022) I-Nicotinamide Mononucleotide Igaywe Ngokuphephile futhi Yehlisa Ngokuphawulekayo Amazinga e-Triglyceride Egazi Kubantu Abanempilo.I-Cureus 14(9): e28812.doi:10.7759/cureus.28812
Isikhathi sokuthumela: Nov-11-2022